Karin wants to be with Sasuke right she will even get alone with Suigetsu if they start to fight she will either try and help or most likely make a run for it either way she will get involve because Kisame is not going to let her pass...
Then the BIG GUY if he gets involve all hell is going to brake loose for both sides
i can see them taking the fight to Kisame but however
seeing Kisame at 100% do the have a chance
I voted kisame