Itachi will die next, either by Sasuke's hands (Itachi has been slowly weakening over the years after all, it could happen) or in the presense of sasuke after Itachi tells sasuke everything.
1) Itachi is not responsible for the death of his clan, he was framed(tobi)
2) He lead everyone to believe(especially sasuke) that he was respobsible for the slaughter
3) Like sasuke, itachi is filled with vengence and seeks only to avenge his clan and family
4) Joining akatsuki gives him the best chance to track down the one responsible
5) Realize's that he is not strong enough to avenge the clan himself, he turns to sasuke and feeds his anger and hate, goading him to become stronger than himself, so that he might succeed where itachi has failed(gimped arm)
6) Yes i know how far fetched that idea is, but i really want that to happen, and hey... we all watch anime and read manga here... stranger things HAVE happened
First post here btw, HI EVERYONE! =D