Quote Originally Posted by artifice View Post
I don't buy the concept that Hashirama was just god gifted with his powers, I think he must have done something to activate them. We know that Hashirama was married to an Uzumaki from the Wirlpool nation a clan known for there powerful sealing abilities and a clan that is also closely connected to the Rikudou. I think it is quite likely that it was Hashirama's wife who helped him unlock his bloodline somehow. We have already seen that the Uzumaki had capabilities powerful enough to merit their destruction. Perhaps it was the Uzumaki who sealed away the Mokuton ability and so their knowledge was necessary to unlock it or perhaps she was able to some how fulfill the missing link between the clans. The Uzumaki as a whole seems to have more in common with the Younger Son of the Rikudou so likely the Senju Bloodline if fractured and only by uniting with an Uzumaki can a Senju awaken their true power. Just like how the Uchiha learned the secrets of their eyes from the Uchiha tablet, I believe a similar tablet likely existed in the Wirlpool village.
Although it is weird, that Tobirama didn't develop Mokuton, your theory would make Yamato more skilled than Tobirama. That, I do not believe.

Quote Originally Posted by artifice View Post
It seems quite likely that it was Madara himself who destroyed the Uzumaki clan and that is partly why the Second Hokage fears him so much.
It's a possibility.

Quote Originally Posted by artifice View Post
If Itachi explored the ruins of the Wirlpool village and learned some of the secrets of the origin of the clans it would explain his understanding and commitment to the big picture. If Madara destroyed the Uzumaki clan and the Wirlpool village their knowledge of the origin of the clans would have been lost with them decreasing the chances of others learning what he had learned. Madara somehow knew about the Origin of the bloodlines and the connections between, I believe that is how he learned a lot of the secrets about the potential of the the bloodlines. I believe that the Wirlpool nation likely had the knowledge of how the bloodlines could be combined. That is also likely where Madara learned that the Uzumaki would be a good host for the Rinnegan.
You are speculating a lot here, there are many IFs. But you are right, Uzumaki Nagato can use his Rinnegan better than Kakashi his Sharingan. Kakashi's Sharingan cannot be switched off, and it constantly drains his power when it's not covered. Meanwhile, Nagato had to activate his Rinnegan, although we never saw his Rinnegan switched off once it was awakened. So there is a good chance the Uzumaki-Clan has an advantage when it comes to taking over doujutsus.

Quote Originally Posted by artifice View Post
Orochimaru can likely restrict them without blocking their personalities though, Kabuto did it with several of the people he revived. You are right in saying that he probably has a plan, he had their genetic information on hand so its likely that he has thought this through quite well. He has probably set it so that he can take control if their is a need. I highly doubt that he has left the cooperation of the Hokages to chance.
No, he wouldn't leave it to chance. Yet it wouldn't be the first time Orochimaru takes risks just for the fun of it. He provoqued Naruto until he went four-tails, and it wasn't easy for Oro to survive the fight that followed. He was absolutely sure the Third had nothing that could cause him trouble, but he did. In the end, Sarutobi rendered his arms useless for quite some time. So maybe Oro is convinced he is prepared, but it's entirely possible that these four have something up their sleeve he doesn't know about. Wouldn't be the first time.