Naruto will do that to Sasuke in their upcoming confrontation. Assuming this is true, then the consequences of the dispute between the younger brother and elder brother are three-fold. The first being that their respective clans would form based on opposing ideology, ensuring that conflict is inevitable and sustained. Through the conflicts caused by that, loved ones will be lost and the "curse" will subsequently over take the Uchiha. The clan rivalry ensures that inter-breeding doesn't occur thus the cycle takes form and the Uchiha's genetic curse actively sustains itself until of course Naruto changes that.